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The crew focused on blocking a protein named synaptotagmin-2, or Syt2. Syt2 is identified to the area of your granules made up of mucin. Fusion of those granules Using the cell membrane depends upon Syt2 interacting with proteins within the mobile membrane.

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In response to your sign while in the cell, these granules fuse With all the cell membranes to launch mucin into your airways. There, mucin interacts with water and salts to build mucus. If an excessive amount mucin is introduced way too quickly, it might overwhelm the readily available water. This creates mucus that is definitely also thick and clogs airways.

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